With a My NCBI account, you can:
Detailed help on setting up and using your My NCBI account is available in the My NCBI Help ebook. NCBI has also posted several short instructional videos showing how to use various features of MyNCBI to YouTube.
In any NCBI database, such as PubMed, click the Sign in to NCBI link on the upper right of the page. On the next screen, click Register for an NCBI account.
After you set up an account, you can customize your My NCBI page and set preferences.